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Circulating Cell-free DNA and Interleukin-6 Expression Following Acute High-Intensity Interval Exercise in Obesity

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Date Issued:
2017
Summary:
The primary purpose of this study was to examine the impact of acute highintensity interval Exercise (HIIE) on plasma cfDNA and IL-6 responses in obese and normal-weight subjects. Fifteen subjects (8 obese and 7 normal-weight) were recruited to participate in an acute HIIE protocol. Our results demonstrated a significant elevation across time in plasma cfDNA and IL-6 immediately following acute HIIE, with no difference between obese and normal-weight subjects. Furthermore, cfDNA was not correlated with IL-6 in response to acute HIIE in either group. These findings indicate that the obese state does not further exacerbate the release of acute HIIE-induced inflammatory mediators (cfDNA and IL-6), which suggests that HIIE training may serve as a time-effective exercise strategy to improve obesity-associated inflammation.
Title: Circulating Cell-free DNA and Interleukin-6 Expression Following Acute High-Intensity Interval Exercise in Obesity.
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Name(s): Ferrandi, Peter J., author
Huang, Chun-Jung, Thesis advisor
Florida Atlantic University, Degree grantor
College of Education
Department of Exercise Science and Health Promotion
Type of Resource: text
Genre: Electronic Thesis Or Dissertation
Date Created: 2017
Date Issued: 2017
Publisher: Florida Atlantic University
Place of Publication: Boca Raton, Fla.
Physical Form: application/pdf
Extent: 68 p.
Language(s): English
Summary: The primary purpose of this study was to examine the impact of acute highintensity interval Exercise (HIIE) on plasma cfDNA and IL-6 responses in obese and normal-weight subjects. Fifteen subjects (8 obese and 7 normal-weight) were recruited to participate in an acute HIIE protocol. Our results demonstrated a significant elevation across time in plasma cfDNA and IL-6 immediately following acute HIIE, with no difference between obese and normal-weight subjects. Furthermore, cfDNA was not correlated with IL-6 in response to acute HIIE in either group. These findings indicate that the obese state does not further exacerbate the release of acute HIIE-induced inflammatory mediators (cfDNA and IL-6), which suggests that HIIE training may serve as a time-effective exercise strategy to improve obesity-associated inflammation.
Identifier: FA00004929 (IID)
Degree granted: Thesis (M.S.)--Florida Atlantic University, 2017.
Collection: FAU Electronic Theses and Dissertations Collection
Note(s): Includes bibliography.
Subject(s): Interval training--Physiological aspects.
Exercise--Physiological aspects.
Physical education and training--Measurement.
Gene expression.
Cellular control mechanisms.
Held by: Florida Atlantic University Libraries
Sublocation: Digital Library
Links: http://purl.flvc.org/fau/fd/FA00004929
Persistent Link to This Record: http://purl.flvc.org/fau/fd/FA00004929
Use and Reproduction: Copyright © is held by the author, with permission granted to Florida Atlantic University to digitize, archive and distribute this item for non-profit research and educational purposes. Any reuse of this item in excess of fair use or other copyright exemptions requires permission of the copyright holder.
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Host Institution: FAU
Is Part of Series: Florida Atlantic University Digital Library Collections.