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EFFECT OF PROXIMITY TO FAILURE IN RESISTANCE TRAINING ON CIRCULATING LEVELS OF NEUROPROTECTIVE BIOMARKERS
| Title: | EFFECT OF PROXIMITY TO FAILURE IN RESISTANCE TRAINING ON CIRCULATING LEVELS OF NEUROPROTECTIVE BIOMARKERS. |
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| Name(s): |
Benitez, Brian, author Zourdos, Michael C. , Thesis advisor Florida Atlantic University, Degree grantor Department of Exercise Science and Health Promotion Charles E. Schmidt College of Science |
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| Type of Resource: | text | |
| Genre: | Electronic Thesis Or Dissertation | |
| Date Created: | 2021 | |
| Date Issued: | 2021 | |
| Publisher: | Florida Atlantic University | |
| Place of Publication: | Boca Raton, Fla. | |
| Physical Form: | application/pdf | |
| Extent: | 66 p. | |
| Language(s): | English | |
| Abstract/Description: | This study examined the acute and chronic responses of brain-derived neurotrophic factor (BDNF), cathepsin B (CatB), insulin-like growth factor-1 (IGF-1), and interleukin-6 (IL-6) and if changes in these biomarkers were correlated during resistance training. Fourteen resistance trained men performed resistance training 3 days per week for 6 weeks in two groups. The only difference between groups was the proximity to failure of each set (4-6 repetitions in reserve or 1-3 repetitions in reserve). Serum was collected immediately before and after training on day 1 of weeks 1 and 6. There were no significant group interactions for any of the biomarkers assessed, there were no main effects for time (p>0.05), and no significant correlations were observed between any of the biomarkers. However, a significant main effect for exercise for BDNF (p=0.03) and IL-6 (p=0.003) was observed. For CatB, a significant exercise × time (p=0.002) interaction was observed, indicating differences in the acute change of CatB in week 6 (+15.78%; g=0.25) vs. week 1 (-7.46%; g=0.13). In summary, these results suggest that multi-joint resistance exercise far from failure can confer a BDNF response. This investigation is the first to demonstrate the potential for acute resistance exercise to elicit a transient increase in CatB. | |
| Identifier: | FA00013751 (IID) | |
| Degree granted: | Thesis (M.S.)--Florida Atlantic University, 2021. | |
| Collection: | FAU Electronic Theses and Dissertations Collection | |
| Note(s): | Includes bibliography. | |
| Subject(s): |
Resistance Training Neuroprotection Biomarkers |
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| Persistent Link to This Record: | http://purl.flvc.org/fau/fd/FA00013751 | |
| Use and Reproduction: | Copyright © is held by the author with permission granted to Florida Atlantic University to digitize, archive and distribute this item for non-profit research and educational purposes. Any reuse of this item in excess of fair use or other copyright exemptions requires permission of the copyright holder. | |
| Use and Reproduction: | http://rightsstatements.org/vocab/InC/1.0/ | |
| Host Institution: | FAU | |
| Is Part of Series: | Florida Atlantic University Digital Library Collections. |
