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Antiviral Activity of Metal-Containing Polymers—Organotin and Cisplatin-Like Polymers
| Title: | Antiviral Activity of Metal-Containing Polymers—Organotin and Cisplatin-Like Polymers. |
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| Name(s): |
Roner, Michael R., author Carraher, Charles E., author Shahi, Kimberly, author Barot, Girish, author |
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| Type of Resource: | text | |
| Genre: | Article | |
| Date Issued: | 2011-05-27 | |
| Summary: | Polymers containing platinum and to a lesser extent tin, have repeatedly demonstrated antitumor activity in vitro and in vivo against a variety of cell and tumor types. The mechanisms responsible for the antitumor activity include inducing a delay in cell proliferation and sister chromatid exchanges blocking tumor growth. As most DNA and some RNA viruses require, and even induce, infected cells to initiate DNA replication and subsequent cell division, compounds with antitumor activity will very likely also possess antiviral activity. This article examines the use of metal-containing polymers as a novel class of antivirals. | |
| Identifier: | 10.3390/ma4060991 (doi), http://www.mdpi.com/1996-1944/4/6/991/ (uri), FAUIR000008 (IID) | |
| Persistent Link to This Record: | http://purl.flvc.org/fau/fd/FAUIR000008 | |
| Use and Reproduction: | publisher | |
| Host Institution: | FAU | |
| Is Part Of: |
Materials. 1996-1944 |
