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Antifungal activity of meridine, a natural product from the marine sponge Corticium sp.
| Title: | Antifungal activity of meridine, a natural product from the marine sponge Corticium sp. |
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| Name(s): |
McCarthy, Peter J., creator Pitts, Tara P., creator Gunawardana, G. P., creator Kelly-Borges, M., creator Pomponi, Shirley A., creator |
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| Type of Resource: | text | |
| Genre: | Article | |
| Issuance: | single unit | |
| Date Issued: | 1992 | |
| Publisher: | The American Chemical Society and American Society of Pharmacognosy | |
| Extent: | 6 p. | |
| Physical Description: | ||
| Language(s): | English | |
| Identifier: | 3333005 (digitool), FADT3333005 (IID), fau:6205 (fedora), 10.1021/np50089a016 (doi) | |
| Note(s): |
Meridine [1], a polycyclic alkaloid derived from the marine sponge Corticium sp., was found to inhibit the growth of Candida albicans and Cryptococcus neoformans. Activity was also observed against Trichophyton mentagrophytes and Epidermophyton floccosum. Studies of the mechanism of action of this agent have shown an inhibition of nucleic acid biosynthesis. This document is the accepted manuscript version of a published work that appeared in final form in Journal of Natural Products after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.1021/np50089a016. This article may be cited as: McCarthy, P. J., Pitts, T. P., Gunawardana, G. P., Kelly-Borges, M., & Pomponi, S. A. (1992). Antifungal activity of meridine, a natural product from the marine sponge Corticium sp. Journal of Natural Products, 55(11), 1664-1668. doi:10.1021/np50089a016 Florida Atlantic University. Harbor Branch Oceanographic Institute contribution #929. |
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| Subject(s): |
Sponges Alkaloids Marine natural products Antifungal agents |
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| Persistent Link to This Record: | http://purl.flvc.org/FCLA/DT/3333005 | |
| Links: | http://dx.doi.org/10.1021/np50089a016 | |
| Restrictions on Access: | ©1992 The American Chemical Society and American Society of Pharmacognosy | |
| Host Institution: | FAU |
